Abstract

The observed variations in three spectral regions of the laser-induced surface fluorescence emission of normal and malignant samples were studied in vivo and in vitro. In the in vivo study spectra were taken during standard surgical operations for the removal of malignant tissue (Ovarian tumors, uterine tumors). In the in vitro study tissue samples were obtained during laparotomy and hysterectomy of women pelvis. In this case the samples were tested in an unfixed state within 2 hours of excision. In all cases samples were then stored in formalin. Histologic examination followed and the results were compared with the surface fluorescence measurements. The experimental apparatus is shown below as well as two typical spectra taken in vivo from a normal and a malignant tissue. The low intensity spectrum comes from the latter.

© 1996 IEEE