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Using the ultraviolet laser beam for control of radio-protective effect during the action of hard ionizing radiation on DNA macromolecules

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Abstract

Combined effects of UV-laser radiation and hard ionizing radiation (neutrons, X(γ)-quantum) on depolymerisation, repairing and stability of DNA are studied. The investigations have been aimed at determining die conditions under which double breakages of DNA macromolecules chains (owing to detrimental action of hard radiation) become self-eliminable when the UV-laser radiation helps to recover the viability of the biosystem. Strict quantum-electrodynamic considerations suggest that die forces of interaction between the two nucleotides on die opposite sites of a break are totally under the control of the width of the break L as well as of dispersion features of dielectric permeabilities εi(ω) of die nucleotides (Adenine, Thymine, Cytosine, Guanine) and intermolecular salt-aqueous medium ε3(ω) through all the range of frequencies.

© 1998 IEEE

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