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  • CLEO/Europe and IQEC 2007 Conference Digest
  • (Optica Publishing Group, 2007),
  • paper CL4_4

Time-correlated Two-photon Fluorescence Imaging with Arrays of Solid-state Single Photon Detectors

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Abstract

This paper reports on our progress in developing multibeam two-photon fluorescence lifetime imaging microscopy (FLIM) based on time-correlated single-photon counting (TCSPC). The core of the system is a 2D array of solid-state single-photon avalanche diodes (SPADs) operating simultaneously and at room temperature. To the best of our knowledge, this is the first solid-state demonstration of a two-photon multichannel FLIM system with a time resolution of 120ps.

© 2007 IEEE

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