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Conferences > CLEO_Europe > 2007 > CL4 > CL4_6
  • CLEO/Europe and IQEC 2007 Conference Digest
  • (Optica Publishing Group, 2007),
  • paper CL4_6

Assessing the binding mode of ligands to DNA by time resolved fluorescence

L. Nardo, M. Bondani, and A. Andreoni

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Abstract

Being able to determine the binding mode of a ligand to DNA, typically base intercalation (BI) or minor groove binding (MGB), is critical to determine the ligand therapeutic effects. Still, drug designers can only gain such information by means of indirect, complicated and very expensive methods [1].

© 2007 IEEE

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