Abstract
Advances in nano- and microscale imaging, medical diagnostics and remote sensing require powerful, versatile and reliable laser sources, particularly in the near- and mid-infrared spectral region. Among biomedical imaging techniques, Stimulated Raman Scattering (SRS) is a very promising tool for label-free identification of chemical components in tissues and cells based on their characteristic vibrational response. In contrast to Coherent Anti-Stokes Raman Scattering (CARS), SRS provides a signal that is linear with molecular concentration and free from non-resonant background [1]. SRS requires two synchronized pulse trains with tunable frequency difference, at high repetition rate (≈100 MHz) and output power >100 mW per branch. Optical parametric sources, in particular the widely used optical parametric oscillators (OPO), naturally provide frequency tunability, but are often complex, costly, and, due to various degrees of freedom, difficult to control.
© 2015 IEEE
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