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  • Conference on Lasers and Electro-Optics/Europe (CLEO/Europe 2023) and European Quantum Electronics Conference (EQEC 2023)
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper ch_10_1

Computational fluorescence imaging with multi-core fiber bundles – Towards high-speed imaging through bare optical fibers

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Abstract

Wavefront control of the coherent lasers has opened a new class of imaging techniques through optical fibers called lensless endoscopes. A spatial light modulator (SLM) at the entrance of an optical fiber modifies the wavefront of a laser beam to undo the scrambling of the initial beams by the fiber and this enables the transport of either illumination patterns or images through the fiber [1]. In the most common implementation, the SLM allows for the generation and the scanning of a single high-intensity focus at the distal end of the fiber with no additional optical elements, analogous to a confocal scanning microscope. This allows for the acquisition of images at a rate only limited by the update rate of the SLM (ranging from a few Hz to ~ kHz). This is relatively slow compared to a confocal microscope where pixel dwell times in the μs regime are routinely obtained. Hence, it remains a significant challenge to speedup the image acquisition rates with lensless endoscopes.

© 2023 IEEE

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