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Conferences > CLEO_Europe > 2023 > cl_6 > cl_6_4
  • Conference on Lasers and Electro-Optics/Europe (CLEO/Europe 2023) and European Quantum Electronics Conference (EQEC 2023)
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper cl_6_4

High-resolution Multiscale Imaging of Unstained Histological Paraffin Embedded Tissue Blocks with Hyperspectral Stokes Polarimetry

Alexander Bykov, Oleksii Siery, Viktor Dremin, Mariia Borovkova, and Igor Meglinski

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Abstract

Bulk tissue polarimetry is a promising method for label-free imaging of biological samples utilizing naturally accrued polarization contrast of structural tissue composition exploiting vector nature of the light [1, 2]. Besides, the hyperspectral imaging is an emerging diagnostic modality widely used for functional tissue characterization [3]. We develop an approach utilizing a combined use of polarization and hyperspectrally-resolved imaging for the non-destructive label-free screening of the paraffin embedded tissue blocks.

© 2023 IEEE

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