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Conferences > CLEO_SI > 2013 > ATu1N > ATu1N.5

Red-Emitting Substrates for Rapid Botulinum Neurotoxin Detection

James N. Herron, Konrad H. Engelhardt, and Vlad O’Mel

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Abstract

We report a new red-emitting molecular beacon for botulinum neurotoxin A suitable inexpensive rapid assay formats. Reaction kinetics including parameters like Km and Vmax were evaluated in a fluorogenic assay using the BoNT/A light chain.

© 2013 Optical Society of America

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