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Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

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Abstract

We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries

© 2015 Optical Society of America

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