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Optical fluorescence to assess abnormal tryptophan metabolic activity in brain samples from Alzheimer’s patients

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Abstract

Brain samples from Alzheimer’s patients and aged-matched controls were studied using label-free fluorescence. Increased tryptophan metabolite to tryptophan ratios were seen in the hippocampus and Brodmann’s area 9 in Alzheimer’s patients as compared to normal.

© 2018 The Author(s)

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