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Enhanced Fluorescence Spectroscopy and Imaging Immunoassay using Biological Photonic Crystals

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Abstract

Utilizing nature-created photonic crystals, diatoms, we developed immunoassay with efficiently enhanced fluorescence signals. Testing on standard antibody-antigen models achieved unprecedented detection limits of 10−16 M and 10−14 M using fluorescence spectroscopy and fluorescence imaging respectively.

© 2018 The Author(s)

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