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Longitudinal Intravital Multi-Photon Imaging of the Femoral Marrow Based on an Implanted GRIN Microendoscope

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Abstract

The development of mechano-optical systems which enable highly resolved, dynamic imaging of the bone marrow of long bones is mandatory to understand patho-physiologic phenomena within this important organ. Here we present a longitudinal intravital microendoscopic technology based on GRIN optics to image one and the same region of the mouse femoral bone marrow over up to 158 days.

© 2018 The Author(s)

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