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Tomographic Diffraction Microscopy : Improving marker-free microscopy resolution using holograms and numerical reconstructions

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Abstract

While the resolution of fluorescence microscopy has undergone a significant improvement in the recent years, reaching a few tens of nanometers [1], that of marker-free microscopes remains stuck at several hundreds of nanometers. Near-field probes and perfect lens concepts permit to break this limit, but this is done at the expense of the ease of use and applicability [2,3].

© 2016 Optical Society of America

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