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Snapshot multi-PSF 3D single-molecule localization microscopy using deep learning

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Abstract

We propose a neural point spread function (PSF) engineering approach for 3D single-molecule localization microscopy. Our approach jointly optimizes the PSFs of multiple optical paths in a microscope with a differentiable localization algorithm.

© 2020 The Author(s)

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More Like This
3D Single Molecule Localization Microscopy via Deep Learning

Xiaoxu Li, Runzhao Yang, Yuchen Guo, Hui Qiao, and Qionghai Dai
MW2A.4 Microscopy Histopathology and Analytics (Microscopy) 2020

Three-Dimensional Localization Microscopy by Deep Learning

Elias Nehme, Boris Ferdman, Daniel Freedman, Lucien E. Weiss, Racheli Gordon-Soffer, Tal Naor, Reut Orange Kedem, Onit Alalouf, Tomer Michaeli, and Yoav Shechtman
3W3G.5 3D Image Acquisition and Display: Technology, Perception and Applications (3D) 2021

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Boris Ferdman, Elias Nehme, Lucien E. Weiss, Reut Orange, and Yoav Shechtman
JW2A.3 CLEO: Applications and Technology (CLEO_AT) 2020

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