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Visible Inverse Spectroscopic Optical Coherence Tomography Probe for Spatially Resolved Nanoscale Characterization

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Valuable diagnostic markers sensitive to the physical nanoscale structural changes present in field carcinogenesis can be obtained using Inverse Spectroscopic Optical Coherence Tomography (ISOCT). In order to perform ISOCT measurements in vivo an achromatic visible OCT probe is required. Here we show a unique radial scanning achromatic visible probe design utilizing doublet lenses capable of obtaining spatially and spectrally resolved optical properties, enabling characterization of mass density fluctuations on nanometer length scales.

© 2016 Optical Society of America

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