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Portable 8-channel time-resolved optical imager for functional studies of biological tissues

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Abstract

We developed a portable dual-wavelength 8-channel system for time-resolved reflectance measurements based on pulsed laser diodes, a multianode photomultiplier and a time-correlated single-photon counting board. The performances of the system were tested on phantoms in terms of stability, reproducibility among channels, and accuracy in the determination of absolute values of the absorption and transport scattering coefficients. Preliminary in vivo measurements (cuff occlusion protocols) were performed on healthy volunteers to monitor spatial changes in tissue oxygenation and blood volume.

© 2001 OSA/SPIE

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