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Improvement of resolution in detection of 3D-functional structures m isolated perfused pig heart

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Abstract

Subcellular structures play a decisive role in light scattering properties of tissue. Our recent efforts aimed at monitoring these structures by use of micro lightguides and scanning tissue spectroscopy technique (EMPHO II SSK) at isolated perfused organs. With application of 70μm lightguides at an isolated perfused pig heart model we were able to improve the resolution to a step size of 20μm.

© 2001 OSA/SPIE

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