Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels

Anastasiya V. Solov'eva; Grigory E. Brill; Ekateryna I. Galanzha; Ekateryna I. Galanzha; Sergey S. Ulyanov; Valery V. Tuchin; Tatiana V. Stepanova; Alexey V. Sedykh

doi:10.1364/ECBO.2001.4434_223

Hybrid and Novel Imaging and New Optical Instrumentation for Biomedical Applications
Technical Digest Series (Optica Publishing Group, 2001),
paper 4434_223
•https://doi.org/10.1364/ECBO.2001.4434_223

Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels

Anastasiya V. Solov'eva, Grigory E. Brill, Ekateryna I. Galanzha, Sergey S. Ulyanov, Valery V. Tuchin, Tatiana V. Stepanova, and Alexey V. Sedykh

European Conference on Biomedical Optics 2001

Munich Germany
18–21 June 2001
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A. V. Solov'eva, G. E. Brill, E. I. Galanzha, S. S. Ulyanov, V. V. Tuchin, T. V. Stepanova, and A. V. Sedykh, "Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels," in Hybrid and Novel Imaging and New Optical Instrumentation for Biomedical Applications, Technical Digest Series (Optica Publishing Group, 2001), paper 4434_223.

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Abstract

In the present study the characteristics of lymph microcirculation are investigated. The lymph microcirculation was studied on small intestine mesentery during N^G-nitro-L-arginine (L-NNA) application on intact microvessels and after stress. The direct measurement of lymph flow velocity (parameter V) in individual microvessels was based on the technique of light intravital videomicroscopy. The first spectral moments of Doppler signal characterizing the mean velocities of lymph flow in microvessels (parameters M_l) were measured by the laser-speckle method. Simultaneously, diameters of lymph microvessels as well as parameters of phasic contractions and valve functioning were registered.

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