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Conferences > ECBO > 2003 > MM > 5139_51

Multiphoton imaging in the detection of malignancy in the oesophagus

Catherine Kendall, Karen McCloskey, Nick Stone, Hugh Barr, and Douglas Greenhalgh

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Abstract

A preliminary investigation of tissue autofluorescence and uptake of the photosensitiser protoporphyrin IX (PpIX) has been investigated using multiphoton imaging of excised oesophageal tissue. The technique has indicated that changes in collagen structure may be a potential marker for high-grade dysplasia and adenocarcinoma. Changes in the localisation of PpIX with the development of malignancy in oesophageal tissue were also visualised.

© 2003 SPIE

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