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Functional optical coherence tomography to reveal functional architecture of cat visual cortex in vivo

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Abstract

Optical intrinsic signal imaging (OISI) provides the surface activation map of brain and has provided many insights. In this study, we show that the optical coherence tomography (OCT) can provide depth resolved functional map of cat visual cortex. Activation profile obtained by integrating OCT signal across depth correlates well with that determined by the OISI. Functional OCT (fOCT) promises to be a valid technique for revealing unexplored organization inside the brain at a micro system level.

© 2003 SPIE

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