Abstract
Fluorescently modified peptide epitopes are applied for detection of p53 antibodies in homogeneous solution. Fluorescence correlation spectroscopy enables simultaneous detection of altered diffusional mobility and confinement of conformational flexibility of the epitopes upon antibody binding.
© 2005 Optical Society of America
PDF ArticleMore Like This
Silvia Scheffler, Denis Strauß, and Markus Sauer
6633_85 European Conference on Biomedical Optics (ECBO) 2007
Dale J. LeCaptain and Alan Van Orden
ThA2 Laser Applications to Chemical and Environmental Analysis (LACSEA) 2002
Utzinger Urs, Kirkpatrick Nathaniel, Brands William, Brewer Molly, and Drezek Rebekah
FTuBB2 Frontiers in Optics (FiO) 2005