The implementation of an isotope-edited internal standard for quantification of lowest drug concentrations using surface enhanced Raman spectroscopy (SERS) in a lab on a chip device

Anne März; Petra Rösch; Thomas Henkel; Jürgen Popp; Jürgen Popp

doi:10.1364/ECBO.2009.7368_0R

Clinical and Biomedical Spectroscopy
Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2009),
paper 7368_0R
•https://doi.org/10.1364/ECBO.2009.7368_0R

The implementation of an isotope-edited internal standard for quantification of lowest drug concentrations using surface enhanced Raman spectroscopy (SERS) in a lab on a chip device

Anne März, Petra Rösch, Thomas Henkel, and Jürgen Popp

European Conference on Biomedical Optics 2009

Munich Germany
14–18 June 2009
ISBN: 9780819476449

From the session
BIOSPECTROSCOPY AND POINT-OF-CARE DIAGNOSTICS II (BPDII)

Not Accessible

Your library or personal account may give you access

Get PDF
Email
Share
Get Citation
Copy Citation Text
A. März, P. Rösch, T. Henkel, and J. Popp, "The implementation of an isotope-edited internal standard for quantification of lowest drug concentrations using surface enhanced Raman spectroscopy (SERS) in a lab on a chip device," in Clinical and Biomedical Spectroscopy, I. Georgakoudi, J. Popp, and K. Svanberg, eds., Vol. 7368 of Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2009), paper 7368_0R.

Export Citation
- BibTex
- Endnote (RIS)
- HTML
- Plain Text
Citation alert
Save article

Abstract

The application of surface enhanced Raman spectroscopy in combination with a microfluidic device and an isotope-edited internal standard seems to be a promising way for a new approach for quantitative SERS measurements. An innovative lab on a chip system offers the possibility for reproducible, quantitative online SERS measurements based on the application of isotope labelled internal standards and liquid/liquid segmented flow based flow-through Raman detection. Errors caused by the used method can be compensated by using an internal standard.

PDF Article

More Like This

The multifunctional application of microfluidic lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) within the field of bioanalytics

Anne März, Bettina Mönch, Angela Walter, Thomas Bocklitz, Wilm Schuhmacher, Petra Rösch, Michael Kiehntopf, and Jürgen Popp
808707 European Conference on Biomedical Optics (ECBO) 2011

Hybrid Photonic Crystal-Plasmonic Lab-on-chip Device using TLC-SERS for Multiple Chemical Sensing

Kundan Sivashanmugan, Kenneth Squire, Boxin Zhang, and Alan X Wang
JW2A.4 CLEO: Applications and Technology (CLEO:A&T) 2020

A portable Surface-Enhanced Raman Spectroscopy platform for biofluid analysis

Sergio Quintero, Maria Relvas, Alexandra Teixeira, Sara Abalde-Cela, and Lorena Diéguez
1262736 European Conference on Biomedical Optics (ECBO) 2023

Previous Article Next Article