Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Effect of Source Decay in Bioluminescence Tomography: A Phantom Study

Not Accessible

Your library or personal account may give you access

Abstract

Recent studies in bioluminescence tomography have been mainly focusing on the ill-posedness and non-uniqueness nature of the problem. In this paper, we demonstrate the significance of the effect of bioluminescence source decay on the reconstruction results with both simulations and phantom studies. Time variation of the bioluminescence source can cause artifacts in the tomographic images. The results show that source dynamic information is pivotal for accurate reconstruction when the decay half-life is comparable to the duration of the data acquisition.

© 2009 OSA/SPIE

PDF Article
More Like This
Multispectral Bioluminescence Tomography: Simulations and Phantom Studies with a priori x-ray CT Spatial Priors

Julius Pekar and Michael S. Patterson
BMB8 Biomedical Optics (BIOMED) 2010

Bioluminescence Tomography Improves Quantitative Accuracy for Pre-Clinical Imaging

James A. Guggenheim, Hector R. A. Basevi, Iain B. Styles, Jon Frampton, and Hamid Dehghani
87990G European Conference on Biomedical Optics (ECBO) 2013

Development of a multi-view, multi-spectral bioluminescence tomography small animal imaging system

James A. Guggenheim, Hamid Dehghani, Hector Basevi, Iain B. Styles, and Jon Frampton
80881K European Conference on Biomedical Optics (ECBO) 2011

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved