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Conferences > ECBO > 2011 > PSIV > 80872L

Method to determine optimal illumination wavelengths for gold nanoparticle detection in tissue using reflectance spectroscopy

P. Beatriz Garcia-Allende, Clement Barriere, Vincent S. Sauvage, Ji Qi, and Daniel S. Elson

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Abstract

A multi-spectral illumination approach for real-time mapping of the presence of gold nanoparticles in bulk tissue is presented. A Principal Component Analysis method is followed for determining the wavelengths that will make up the multispectral imaging endoscope.

© 2011 OSA/SPIE

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