Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study

Antonio Pifferi; Antonio Pifferi; Ilaria Bargigia; Paola Taroni; Paola Taroni; Andrea Farina; Rinaldo Cubeddu; Rinaldo Cubeddu

doi:10.1364/ECBO.2011.808817

Diffuse Optical Imaging III
Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011),
paper 808817
•https://doi.org/10.1364/ECBO.2011.808817

Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study

Antonio Pifferi, Ilaria Bargigia, Paola Taroni, Andrea Farina, and Rinaldo Cubeddu

European Conference on Biomedical Optics 2011

Munich Germany
22–26 May 2011
ISBN: 9780819486851

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A. Pifferi, I. Bargigia, P. Taroni, A. Farina, and R. Cubeddu, "Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study," in Diffuse Optical Imaging III, A. Hielscher and P. Taroni, eds., Vol. 8088 of Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011), paper 808817.

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Abstract

We propose a system for time-domain diffuse optical spectroscopy extending up to 1300 nm based on a supercontinuum source and time-correlated single photon counting detection. The system was validated on liquid phantoms demonstrating a good linearity up to an absorption coefficient of 2.0 cm⁻¹. Preliminary measurements on collagen powder reveal an important absorption peak around 1200 nm. Feasibility of in vivo diffuse optical spectroscopy on the female breast is demonstrated up to 1200 nm at an interfiber distance of 2 cm.

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