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Three-dimensional image-guided fluorescence using boundary element method and dual reciprocity method

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Abstract

A boundary element method with dual reciprocity method (BEM-DRM) was used to model fluorescence in tissue using coupled diffusion equations in 3D. This method eliminates the need for node connectivity in a volume mesh of arbitrary shapes, requiring instead, a surface mesh with interior points to model the fluorescence source in 3D. Results using BEM-DRM show agreement with data from open source finite-element based software package NIRFAST7 with mean error difference of 0.08 for optimally chosen support parameter for radial basis functions used.

© 2011 OSA/SPIE

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