Abstract

We demonstrate the optimization of wavelengths for the imaging of cortical haemoglobin oxygenation with broadband RGB reflectometry. Wavelengths were chosen to minimize the crosstalk and to optimize the signal to noise ratio by simulating the effects of different combinations of wavelengths on the condition number of the resulting extinction coefficients matrices. The results obtained were evaluated for four combinations of commercial available LEDs and the condition number analysis is compared with data from literature.

© 2013 SPIE