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Validation of time domain near infrared spectroscopy in muscle measurements: effect of a superficial layer

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Abstract

In reflectance spectroscopy, a major concern is the possibility to discriminate signals coming from different layers of the investigated medium. In this work, the case of time-domain near infrared spectroscopy of muscle is studied with particular attention in the estimation of the pathlength in the different tissue’s layers and its impact in the calculation of chromophores concentration.

© 2015 SPIE

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