Bessel Beam OCM for analysis of Global Ischemia in Mouse Brain

Mounika Rapolu; Hubert Dolezyczek; Szymon Tamborski; Monika Malinowska; Grzegorz Wilczynski; Maciej Szkulmowski; Maciej Wojtkowski

doi:10.1117/12.2287740

Optical Coherence Imaging Techniques and Imaging in Scattering Media II
SPIE Proceedings (Optica Publishing Group, 2017),
paper 1041609
•https://doi.org/10.1117/12.2287740

Bessel Beam OCM for analysis of Global Ischemia in Mouse Brain

Mounika Rapolu, Hubert Dolezyczek, Szymon Tamborski, Monika Malinowska, Grzegorz Wilczynski, Maciej Szkulmowski, and Maciej Wojtkowski

European Conference on Biomedical Optics 2017

Munich Germany
25–29 June 2017
ISBN: 9781510612907

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Optical Coherence Imaging of Brain Tissue (OCIBT)

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M. Rapolu, H. Dolezyczek, S. Tamborski, M. Malinowska, G. Wilczynski, M. Szkulmowski, and M. Wojtkowski, "Bessel Beam OCM for analysis of Global Ischemia in Mouse Brain," in Optical Coherence Imaging Techniques and Imaging in Scattering Media II, M. Wojtkowski, ed., Vol. 10416 of SPIE Proceedings (Optica Publishing Group, 2017), paper 1041609.

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Abstract

We present the in-vivo imaging of the global mouse brain ischemia using Bessel beam optical coherence microscopy. This method allows to monitor changes in brain structure with extra control of blood flow during the process of artery occlusion. The results show the capability and sensitivity of OCM system with Bessel beam to analyze brain plasticity after severe injury within a period of 8days.

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