Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Comparative analysis of single- and dual-wavelength low dose photodynamic therapy regimens

Not Accessible

Your library or personal account may give you access

Abstract

Dual-wavelength photodynamic therapy is a photodynamic therapy (PDT) modality combining therapeutic effects of irradiation at two wavelengths of different region of visible range. In this paper we report on comparative analysis of single- and dual-wavelength PDT regimes based on multimodal optical monitoring of tissue response with histologic verification. Morphological and functional tissue responses to PDT procedure with chlorin-based photosensitizer (PS) were studied at the normal skin of a rabbit ear inner surface. Multimodal optical monitoring was performed by OCT and dual-wavelength fluorescence technique. The studied doses vary from 50 to 150 J/cm2 delivered separately at 405 or 660 nm, or at both wavelengths together in the equal dose.

© 2019 SPIE/OSA

PDF Article
More Like This
Red and blue light photodynamic therapy regimes: optical monitoring and histology studies

Mikhail Kirillin, Maria Shakhova, Daria Kurakina, Aleksandr Khilov, Anna Orlova, Ekaterina Sergeeva, Alina Meller, Natalia Orlinskaya, and Ilya Turchin
11079_26 European Conference on Biomedical Optics (ECBO) 2019

Low Dose mTHPC Photodynamic Therapy for Cholangiocarcinoma

Herbert Stepp, Gesa Kniebühler, Thomas Pongratz, Christian S. Betz, Burkhard Göke, Ronald Sroka, and Jörg Schirra
88030M European Conference on Biomedical Optics (ECBO) 2013

Dual-wavelength fluorescence localization of chlorin-based photosensitizer

A.V. Khilov, D.A. Kurakina, I.V. Turchin, and M.Yu. Kirillin
11079_54 European Conference on Biomedical Optics (ECBO) 2019

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved