Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Simulations for modeling the photothermal response of nerve tissue

Not Accessible

Your library or personal account may give you access


Optical nerve stimulation (ONS) using infrared laser radiation is a technique developing as a potential alternative to electrical stimulation of nerve tissue. This preliminary study proposes and explores a computer simulation tool for numerically optimizing laser and surface scanning parameters including laser power and surface scanning speed to be used in laser scanning subsurface ONS. This tool consisted of three parts, including the Monte Carlo simulations for generating laser energy distribution in the tissue sample, the laser-scanning model by moving the heat source at the surface, and the thermal transfer simulations to calculate the tissue temperature. In the simulations, the laser wavelength of 1490 nm was used and the surface scan was performed on both x and y axes. In addition, the tissue model was constructed in such a way that the nerve tissue extends over the y-axis. As a result of calculations, the nerve tissue temperature map was produced as a function of laser power and surface scanning speed. According to the temperature map, the optimal laser power to reach the nerve temperature at 43 °C was estimated to be 15 mW at the scanning speeds of 1.2 mm/s in the x-axis and 1.0 mm/s in the y-axis. With further development this simulation tool may hold promise in the development of an optical stimulus device.

© 2019 SPIE/OSA

PDF Article
More Like This
Photothermal modelling of thulium fibre laser-tissue interactions

Catherine E. Warnaby, Daniel J. Coleman, and Terence A. King
5142_68 European Conference on Biomedical Optics (ECBO) 2003

Ex-vivo Model Experimental and Simulation Results Suggesting Effective and Superficial Mucosal Photothermal Ablation at 1505 nm

Merve Turker Burhan, Alper Bagrıyanık, and Serhat Tozburun
ETh2A.8 European Conference on Biomedical Optics (ECBO) 2021

Thermal Modeling and Simulation for Optical Illumination to Extract Cancer Cells from Human Tissue Samples

Chang-Mu Han, Edo Waks, and Benjamin Shapiro
JTu3A.127 Frontiers in Optics (FiO) 2019


You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
Login to access Optica Member Subscription

Select as filters

Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved