Time-domain diffuse correlation spectroscopy performance at different source-detector separation

Neda Mogharari; Saeed Samaei; Stanisław Wojtkiewicz; Adam Liebert; Michał Kacprzak

doi:10.1117/12.2670670

Diffuse Optical Spectroscopy and Imaging IX
Technical Digest Series (Optica Publishing Group, 2023),
paper 1262816
•https://doi.org/10.1117/12.2670670

Time-domain diffuse correlation spectroscopy performance at different source-detector separation

Neda Mogharari, Saeed Samaei, Stanisław Wojtkiewicz, Adam Liebert, and Michał Kacprzak

European Conference on Biomedical Optics 2023

Munich Germany
25–29 June 2023
ISBN: 9781510664654

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Advances in Instrumentation and Technology III (AITIII)

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N. Mogharari, S. Samaei, S. Wojtkiewicz, A. Liebert, and M. Kacprzak, "Time-domain diffuse correlation spectroscopy performance at different source-detector separation," in Diffuse Optical Spectroscopy and Imaging IX, Technical Digest Series (Optica Publishing Group, 2023), paper 1262816.

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Abstract

Time domain diffuse correlation spectroscopy (td-DCS), has been proposed as a method that can increase the sensitivity of DCS for detecting blood flow index (BFI) in deep tissue. Several important parameters including the instrument response function (IRF), gate start time, gate width, and source-detector separation (SDS) must be taken into consideration. In our study, we characterized td-DCS system at three different SDS values and assessed each SDS's ability to detect dynamic changes of blood flow caused by moving red blood cells during cuff occlusion.

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