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Influence of the heterogeneity of extracerebral tissues on scalp-cortex correlation of fNIRS for infants

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Abstract

For the prediction of the scalp-cortex correlation (SCC), it is important to consider the influence of the extracerebral tissues on light propagation in the brain. The three-layered infant head models in which the scalp, skull, and cerebrospinal fluid (CSF) are combined as a homogeneous tissue are constructed in order to investigate the influence of the heterogeneity of the thin extracerebral tissues on the prediction of the SCC of infants. The spatial sensitivity profile in the brain calculated by the three-layered model is less broadened than that by the ordinary five-layered model due to the lack of the low scattering CSF layer. However, the influence of the heterogeneity of the extracerebral tissues on the SCC of infants is less significant than that of an adult. The three-layered head model is practically useful to predict the acceptable SCC of the functional near infrared spectroscopy measurements of infants.

© 2023 SPIE

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