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  • 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference
  • (Optica Publishing Group, 2015),
  • paper JSII_1a_1

Single-Cell Optical Stretching and Sorting into an Integrated Microfluidic Device

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Abstract

Optical stretching emerged in the recent years as a very promising technique for testing mechanical properties of single cells in an efficient and non-destructive way. Several papers already demonstrated that many different pathologies result in changes in cellular deformability, and optical stretching can thus be used as a technique to evaluate the health of unlabelled cells [1]. Up to now, what is still unreported in the current scientific literature is the ability to use a single integrated chip to analyze the stretching response of cells, and to use the measured deformation as a parameter for selective sorting. In this summary we briefly describe the design, fabrication and validation of a similar device.

© 2015 IEEE

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