Designing Interfaces for Optical Biosensors

Ashutosh Chilkoti

doi:10.1364/FIO.2009.FTuY3

Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest
OSA Technical Digest (CD) (Optica Publishing Group, 2009),
paper FTuY3
•https://doi.org/10.1364/FIO.2009.FTuY3

Designing Interfaces for Optical Biosensors

Ashutosh Chilkoti

Frontiers in Optics 2009

San Jose, California United States
11–15 October 2009
ISBN: 978-1-55752-878-0

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Optical Biosensing (FTuY)

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A. Chilkoti, "Designing Interfaces for Optical Biosensors," in Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, OSA Technical Digest (CD) (Optica Publishing Group, 2009), paper FTuY3.

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Abstract

I will describe two interfaces for optical biosensors: (1) a label-free biosensor that exploits the local surface plasmon resonance of noble metal nanostructures; and (2) a polymer brush interface on glass that abolishes non-specific adsorption leading to a femtomolar limit-of-detection of protein analytes in whole blood.

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