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Three-Dimensional Fourier-Transform Second-Harmonic Generation Microscopy for Quantification of Collagen Fiber Organization in Biological Tissues

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Abstract

Fourier transform-second harmonic generation imaging has previously been shown to be useful in quantifying collagen fiber organization in 2D. Here, we generalize this approach to 3D and calculate preferred fiber orientations for porcine sclera.

© 2012 Optical Society of America

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More Like This
Fourier transform-second-harmonic generation imaging of collagen fibers in biological tissues

Raghu Ambekar Ramachandra Rao, Monal R. Mehta, Scott Leithem, and Kimani C. Toussaint
BSuD63 Biomedical Optics (BIOMED) 2010

Real-time Fourier Transform-Second-Harmonic Generation Imaging of Collagen-based Biological Tissues

Tung-Yuen Lau, Mohammad M. Kabir, Veera V. G. K. Inavalli, and Kimani C. Toussaint
QW3G.3 Quantitative Medical Imaging (QMI) 2013

Quantitative metrics for SHG imaging of collagen-based biological structures

Tung Yuen Lau and Kimani C. Toussaint
NT1B.4 Novel Techniques in Microscopy (NTM) 2013

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