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Conferences > FiO > 2015 > FTu5B > FTu5B.4

Polarization Imaging in the Retina of a Dog Model of Alzheimer's Disease Enables Discrimination of Amyloid Deposits

Melanie C.W. Campbell, David DeVries, Theodore Chow, Laura Emptage, Namrata Shah, Howard Dobson, Christopher Cookson, and Marsha Kisilak

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Abstract

Beagle dogs suffer from a naturally occurring cognitive dysfunction syndrome, with symptoms and brain pathology similar to Alzheimer’s disease. We show that polarization imaging correctly classifies 95% of amyloid deposits from surrounding retina in diseased dogs.

© 2015 Optical Society of America

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