Protein Crystal Structure Determination and Radiation Damage at a dose of 3 GGy using a Free-Electron Laser

Lukas Lomb; Lukas Lomb; Thomas R.M. Barends; Thomas R.M. Barends; Ilme Schlichting; Ilme Schlichting

doi:10.1364/HILAS.2012.HM2C.1

Research in Optical Sciences
OSA Technical Digest (Optica Publishing Group, 2012),
paper HM2C.1
•https://doi.org/10.1364/HILAS.2012.HM2C.1

Protein Crystal Structure Determination and Radiation Damage at a dose of 3 GGy using a Free-Electron Laser

Lukas Lomb, Thomas R.M. Barends, and Ilme Schlichting

High Intensity Lasers and High Field Phenomena 2012

Berlin Germany
19–21 March 2012
ISBN: 978-1-55752-939-8

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Short Wavelength Sources and Applications (HM2C)

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L. Lomb, T. R. M. Barends, and I. Schlichting, "Protein Crystal Structure Determination and Radiation Damage at a dose of 3 GGy using a Free-Electron Laser," in Research in Optical Sciences, OSA Technical Digest (Optica Publishing Group, 2012), paper HM2C.1.

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Abstract

Radiation damage induced by 2 keV femtosecond X-ray pulses was studied in protein microcrystals as a function of pulse length and fluence. Dose and dose rate dependent effects were observed, suggesting the occurrence of “hotspots” for damage.

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