Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Integrated Photonics Research, Silicon and Nanophotonics and Photonics in Switching
  • OSA Technical Digest (CD) (Optica Publishing Group, 2010),
  • paper IME7
  • https://doi.org/10.1364/IPRSN.2010.IME7

Silicon Wire Waveguide Label-free Biosensor Arrays

Not Accessible

Your library or personal account may give you access

Abstract

We report multiplexed label-free measurements of biomolecular interactions using silicon wire waveguide sensor arrays. The sensors are addressed using both wavelength division multiplexing and power broadcasting approaches. We demonstrate the real-time monitoring of antibody-antigen reactions using complementary and mismatched IgG receptor-analyte pairs and bovine serum albumin. The measured level of detection for each sensor element corresponds to a surface coverage of less than ~ 0.02% of a protein monolayer. The two addressing approaches are compared.

© 2010 Optical Society of America

PDF Article
More Like This
Spiral Cavity Si Wire Resonators as Label-free Biosensors

D.-X. Xu, A. Densmore, J. H. Schmid, R. Ma, M. Vachon, S. Janz, R. McKinnon, J. Lapointe, A. Delâge, E. Post, and P. Cheben
IMB2 Integrated Photonics and Nanophotonics Research and Applications (IPR) 2009

Waveguide biosensor with integrated photodetector array for tuberculosis serology

Rongjin Yan, N. Scott Lynn, Luke C. Kingry, David S. Dandy, Richard A. Slayden, and Kevin L. Lear
AMC4 Conference on Lasers and Electro-Optics: Applications (CLEO:A&T) 2010

High-Contrast Grating Resonator for Label-Free Biosensors

Tianbo Sun, Shu Kan, Gerard Marriot, and Connie Chang-Hasnain
STu4K.6 CLEO: Science and Innovations (CLEO:S&I) 2015

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved