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Optica Publishing Group
  • International Quantum Electronics Conference
  • OSA Technical Digest (Optica Publishing Group, 1984),
  • paper FB5

Mechanisms of the Hematoporphyrin-Derivative-Induced Photodamage of Neoplastic Cells: Fluorescence Studies

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This work reports on studies of spectral properties and fluorescence decay times of hematoporphyrin derivative (HpD). The dependence of these parameters on physicochemical and biological conditions has been studied in solution, in cells, and in culture medium. Particular attention was devoted to the presence of a HpD emission band in the 570–590-nm range. This band does not naturally occur in fresh HpD solution and seems more likely in tumor than in normal HpD-treated cells.

© 1984 Optical Society of America

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