Imaging chemical environments and amyloid architectures using single-molecule orientation-localization microscopy

Tianben Ding; Jin Lu; Tingting Wu; Matthew D. Lew

doi:10.1364/ISA.2021.ITu7A.6

OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP)
OSA Technical Digest (Optica Publishing Group, 2021),
paper ITu7A.6
•https://doi.org/10.1364/ISA.2021.ITu7A.6

Imaging chemical environments and amyloid architectures using single-molecule orientation-localization microscopy

Tianben Ding, Jin Lu, Tingting Wu, and Matthew D. Lew

Imaging Systems and Applications 2021

Washington, DC United States
19–23 July 2021
ISBN: 978-1-943580-89-7

From the session
Biomedical Imaging II (ITu7A)

Not Accessible

Your library or personal account may give you access

Get PDF
Email
Share
Get Citation
Copy Citation Text
T. Ding, J. Lu, T. Wu, and M. D. Lew, "Imaging chemical environments and amyloid architectures using single-molecule orientation-localization microscopy," in OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP), H. Hua, B. Javidi, M. Martinez-Corral, O. Matoba, A. Stern, S. Thibault, T. Alieva, J. Ke, F. Willomitzer, F. Okten, P. Silveira, P. Banerjee, E. Stoykova, D. Chu, J. Park, F. Imai, C. Joo, M. Digman, D. Gardner, S. Gladysz, D. LeMaster, S. Basu, and O. Korotkova, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper ITu7A.6.

Export Citation
- BibTex
- Endnote (RIS)
- HTML
- Plain Text
Get Video
Citation alert
Save article

Abstract

We demonstrate various point spread functions that produce superior performance for single-molecule orientation-localization microscopy. These orientation “spectra” reveal chemical environments and amyloid architectures that cannot be visualized using traditional super-resolution microscopy.

PDF Article | Presentation Video

More Like This

Robustly detecting imaging model mismatches and reconstruction artifacts in single-molecule localization microscopy

Hesam Mazidi, Tianben Ding, Arye Nehorai, and Matthew D. Lew
CTu4B.5 Computational Optical Sensing and Imaging (COSI) 2021

Snapshot multi-PSF 3D single-molecule localization microscopy using deep learning

Hayato Ikoma, Yifan Peng, Michael Broxton, and Gordon Wetzstein
CW3B.3 Computational Optical Sensing and Imaging (COSI) 2020

Investigating amyloid nucleation and growth using single molecule fluorescence microscopy

Keith M. Berland, David G. Lynn, and Yan Liang
LSThB1 Laser Science (LS) 2009

Previous Article Next Article

Presentation Video

Presentation video access is available to:

Optica Publishing Group subscribers
Technical meeting attendees
Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads