Simultaneous superficial cortex and deep brain imaging in mice brain using wide-field microscope through implanting custom-built cranial window

Chaowei Zhuang; Rujin Zhang; Rujin Zhang; Guihua Xiao; Guihua Xiao; Jiangbei Cao; Hao Xie; Hao Xie; Qionghai Dai; Qionghai Dai; Qionghai Dai

doi:10.1364/ISA.2021.ITu7A.7

OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP)
OSA Technical Digest (Optica Publishing Group, 2021),
paper ITu7A.7
•https://doi.org/10.1364/ISA.2021.ITu7A.7

Simultaneous superficial cortex and deep brain imaging in mice brain using wide-field microscope through implanting custom-built cranial window

Chaowei Zhuang, Rujin Zhang, Guihua Xiao, Jiangbei Cao, Hao Xie, and Qionghai Dai

Imaging Systems and Applications 2021

Washington, DC United States
19–23 July 2021
ISBN: 978-1-943580-89-7

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Biomedical Imaging II (ITu7A)

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C. Zhuang, R. Zhang, G. Xiao, J. Cao, H. Xie, and Q. Dai, "Simultaneous superficial cortex and deep brain imaging in mice brain using wide-field microscope through implanting custom-built cranial window," in OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP), H. Hua, B. Javidi, M. Martinez-Corral, O. Matoba, A. Stern, S. Thibault, T. Alieva, J. Ke, F. Willomitzer, F. Okten, P. Silveira, P. Banerjee, E. Stoykova, D. Chu, J. Park, F. Imai, C. Joo, M. Digman, D. Gardner, S. Gladysz, D. LeMaster, S. Basu, and O. Korotkova, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper ITu7A.7.

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Abstract

We propose an ultra-large field-of-view (FOV) and cellular-resolution wild-field macroscope to show the simultaneous superficial cortex and deep brain imaging by implanting two different custom-built cranial windows: glass plug and microprism.

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