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Photoisomerization of azobenzene derivative combined liposome using a two-photon UV–Blue pulsed laser

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Abstract

Azobenzene-based photo devices have attracted ongoing interest for applications in controlled drug release since the first report by Kano et al. in the early 1980s.[1, 2] However, the poor penetration of UV light which is necessary for chemical structure change of azobenzene limits the in vivo application of azobenzene. In this study, a broadly tunable pulsed laser with a tuning range from the UV to blue region was developed and used for conformational change of the azobenzene derivative.

© 2014 Japan Society of Applied Physics, Optical Society of America

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