Abstract

There is a strong need for low-cost, disposable, label-free biosensors to enable fast, on-site biomedical and chemical detection [1]. Among the various biosensors, guided-mode-resonance (GMR) biosensors have attracted increasing attention for practical biomedical and chemical applications because of the advantages of their simple structure, simple fabrication, and high sensitivity [2]. However, there exist challenges to fabricate sub-wavelength periodic patterns for successful GMR bio-sensors in a cost-efficient way. In our previous works, we have employed injection-molded technique to fabricate GMR biosensors, and demonstrated sensitivity of up to 181.9 nm/RIU [3, 4]. In this paper, we report on a study of polarization-dependent optical responses for the injection-molded GMR (IM-GMR) biosensors.

© 2015 Japan Society of Applied Physics, Optical Society of America