Abstract

Rapid and sensitive detection of proteins, antibodies in biological samples has broad applications including immune response for infectious diseases, cancer, and cardiovascular disease [1]. For instance, cancer biomarker and cancer cells detection have shown great promise in early detection of colon, prostate, and leukemia cancers [2]. The sensing mechanism of the photonic crystal (PhC) is that the effective refractive index of the sensing area is changed by the activation of target biomaterials. Proposed biosensors have been used to detect prostate specific antigen (PSA) that is responsible for prostate cancer. The schematic of proposed device is shown in Fig. 1.

© 2016 Japan Society of Applied Physics, Optical Society of America