Monte Carlo Model of a Single Molecule Counting Experiment

Lloyd M. Davis; Li-Qiang Li

doi:10.1364/LACA.1994.ThD.2

Laser Applications to Chemical Analysis
Technical Digest Series (Optica Publishing Group, 1994),
paper ThD.2
•https://doi.org/10.1364/LACA.1994.ThD.2

Monte Carlo Model of a Single Molecule Counting Experiment

Lloyd M. Davis and Li-Qiang Li

Laser Applications to Chemical Analysis 1994

Wyoming United States
8–11 March 1994
ISBN:

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Single Molecule Detection (ThD)

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L. M. Davis and L. Li, "Monte Carlo Model of a Single Molecule Counting Experiment," in Laser Applications to Chemical Analysis, Technical Digest Series (Optica Publishing Group, 1994), paper ThD.2.

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Abstract

In experiments for fluorescence detection of single molecules in solution the background due to unrejected scattered light increases linearly with laser power while the dye molecule fluorescence signal and photodegradation probability saturate.

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