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Large-scale chemical analysis by laser-induced fluorescence detection and multiple capillary electrophoresis separation

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Abstract

Capillary electrophoresis provides rapid separation of long DNA sequencing fragments. However, it is necessary to operate many capillaries in parallel to compete with slab-gel electrophoresis systems. A number of capillary array instruments have been reported based on a scanning optical detector; these systems suffer from a low detection duty cycle.

© 1998 Optical Society of America

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