Increased Smooth Muscle Actin, Factor XIIIa, and Vimentin positive cells in the papillary dermis of CO2 laser debrided porcine skin

Kathleen J. Smith; Henry G. Skelton; Charles Hurst; Brennie E. Hackley

doi:10.1364/LID.1997.SaB3

Lasers in Dermatology: Bio-Optics and Treatment of Human Skin
Technical Digest Series (Optica Publishing Group, 1997),
paper SaB3
•https://doi.org/10.1364/LID.1997.SaB3

Increased Smooth Muscle Actin, Factor XIIIa, and Vimentin positive cells in the papillary dermis of CO2 laser debrided porcine skin

Kathleen J. Smith, Henry G. Skelton, Charles Hurst, and Brennie E. Hackley

Lasers in Dermatology: Bio-Optics and Treatment of Human Skin 1997

Long Beach, California United States
17–18 October 1997
ISBN:

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K. J. Smith, H. G. Skelton, C. Hurst, and B. E. Hackley, "Increased Smooth Muscle Actin, Factor XIIIa, and Vimentin positive cells in the papillary dermis of CO2 laser debrided porcine skin," in Lasers in Dermatology: Bio-Optics and Treatment of Human Skin, Technical Digest Series (Optica Publishing Group, 1997), paper SaB3.

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Abstract

Skin is a major target for the chemical warface agent sulfur mustard (bis-2-chloroethyl sulfide; HD). Delayed wound healing is seen with HD-induced cutaneous lesions, and was the initial stimulus for our study using a pulsed CO2 laser to potentiate wound healing. Another factor we wanted to determine was what factors present within dermis and/or stromal cell populations therein could account for the tightening of skin seen after pulsed CO2 laser debridement.2-7

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