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  • Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest
  • OSA Technical Digest (CD) (Optica Publishing Group, 2009),
  • paper LSThD3
  • https://doi.org/10.1364/LS.2009.LSThD3

DNA Repair Protein Dynamics through Single-Molecule Fluorescence

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Abstract

Crystal structures of mismatch repair proteins bound to mismatched DNA reveal kinked DNA. With single molecule FRET we observed dynamic switching among different bent states, which suggests the dynamics of bending may influence mismatch repair.

© 2009 APS DLS

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