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Conferences > LS > 2022 > JW4B > JW4B.48

Aptamer-Based Microparticles for Biochemical Sensing Using Optical Coherence Tomography

Shreyas Shah, Quoc Mac, John Kim, and Michael S. Eggleston

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Abstract

We developed a modular approach for biochemical sensing using aptamer-based microparticles and swept-source OCT. Tuning the crosslinker composition of the microparticle enabled varying physicochemical responses to a target biochemical, ranging from degradation to reversible swelling, which was spatiotemporally monitored in tissue-mimics using OCT.

© 2022 The Author(s)

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